What is it about?
Triterpenoids are compounds that draw attentions of scientists because of their wide source, wide variety, high medicinal value, and anti-tumor properties. However, a lack of approach to understand their chemical structures has limited the fundamental comprehension of these compounds in cancer cell therapy.To seek anti-cancer activity of the structures of triterpenoid compounds and their derivatives, we summarized a number of plants and their derivatives that are a source of potential novel therapeutic anti-cancer agents. This work focuses on relevant 1036 patents and references that detail the structure of organic compounds and derivatives for the treatment of tumors. Compared to tetracyclic triterpenoid, pentacyclic triterpenoid is contributed more to improve the autophagic signaling pathways of cancer cells. The heterogenous skeleton structure of triterpenoids impaired the programmed cell death signaling pathway in various cancers
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Why is it important?
The heterogenous skeleton structure of triterpenoids impaired the programmed cell death signaling pathway in various cancers
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This page is a summary of: A Link Between Chemical Structure and Biological Activity in Triterpenoids, Recent Patents on Anti-Cancer Drug Discovery, May 2022, Bentham Science Publishers, DOI: 10.2174/1574892816666210512031635.
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