What is it about?
Anti-obesity Effect of Cold Nanoparticles from Dendropanax morbifera Leveille by Suppression of Triglyceride Synthesis and Davvnregulation of PPAR gamma and CEBP alpha Signaling Pathways in 3T3-L1 Mature Adipocytes and HepG2 Cells
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Why is it important?
We hypothesize that Dendropanax contains a large amount of phenolic compound that coats the surface of gold nanoparticles and has the ability to reduce the excess amount of lipid in both cell lines.
Perspectives
Green synthesized D-AuNPs showed low toxicity in both cell lines examined in this study. This efficacy might be due to reduced particle size. Significantly increased anti-lipid accumulation caused by downregulation of STAT3/PPARγ/CEBPα pathways may have phytochemicals coated to the surface area of gold nanoparticles.
Sunoh Kim
B&Tech Co.Ltd
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This page is a summary of: Anti-obesity Effect of Gold Nanoparticles from Dendropanax morbifera Léveille by Suppression of Triglyceride Synthesis and Downregulation of PPARγ and CEBPα Signaling Pathways in 3T3-L1 Mature Adipocytes and HepG2 Cells, Current Nanoscience, March 2020, Bentham Science Publishers, DOI: 10.2174/1573413716666200116124822.
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