What is it about?
In this review, we have tried to collect the current available information on the mechanism of action of AMPs in synergy with other antimicrobial agents. In particular, we have focused inon the mechanisms of action that mediate AMPs the inhibition by AMPs of emergence of bacterial resistance by AMPs.
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Why is it important?
Antimicrobial peptides can work as adjuvants at non-toxic concentrations and can be safely administrated for novel combined therapies.
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This page is a summary of: Synergism between Host Defence Peptides and Antibiotics Against Bacterial Infections, Current Topics in Medicinal Chemistry, June 2020, Bentham Science Publishers, DOI: 10.2174/1568026620666200303122626.
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