What is it about?

Neurodegenerative diseases (NDDs) are conditions where brain cells continuously break down, leading to the loss of brain functions. These conditions are becoming more common as people live longer. Traditionally, treatments and surgeries for these diseases have had limited success. However, recent advances in understanding NDDs, better ways to deliver drugs, and new targeted medicines have opened up innovative treatment options. These new treatments often need skilled neurosurgery to be applied. We discuss the latest findings and how they're changing the treatment of NDDs. We also discuss how neurosurgery has always played a role in treating these conditions and highlight this in implementing new treatments.

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Why is it important?

The significance of our work lies in its timely response to the escalating prevalence of neurodegenerative diseases (NDDs ) due to the aging global population. Our investigation into novel therapeutic approaches, rooted in the latest advancements in drug delivery systems, disease understanding, and pharmacology, addresses a critical gap in the existing treatment landscape. Traditional methods have often fallen short in managing NDDs effectively, leaving many patients with limited options. By integrating cutting-edge neurosurgical techniques with innovative pharmacological interventions, our work expands the arsenal against NDDs and offers a glimmer of hope for improved patient outcomes. What sets our research apart is its multidisciplinary approach, combining the precision of neurosurgery with the latest in pharmacological research to target NDDs more effectively. This convergence of fields is new and represents a pioneering step forward in the treatment of conditions that have long been considered challenging to manage. The potential impact of our work is significant, offering new pathways for treatment that could slow disease progression, alleviate symptoms, and enhance the quality of life for millions affected by NDDs globally. By pushing the boundaries of current treatment paradigms, our research contributes to the scientific community and holds profound implications for patient care, highlighting the critical importance of innovation in addressing some of the most pressing health challenges of our time.


Struck by the profound sense of purpose and urgency that drove our research of neurodegenerative diseases (NDDs). These diseases are not just a clinical challenge but a deeply human one, affecting individuals and families across the globe. The opportunity to contribute to this field, to light the way to more effective treatments, has been both a privilege and a profound responsibility. Our work is a testament to the power of interdisciplinary collaboration, a reminder that the most complex health challenges require us not only to pool our knowledge and skills but also to think beyond the confines of traditional disciplines. As we share our findings with the wider community, I hope our work inspires further exploration, collaboration, and innovation in the fight against neurodegenerative diseases. The path ahead is undoubtedly complex, but our progress reinforces my belief in our collective ability to confront these challenges with courage, creativity, and a commitment to making a difference in the lives of those who face the realities of NDDs every day.

Majid Khan
University of Nevada Reno

Read the Original

This page is a summary of: Innovative Discoveries in Neurosurgical Treatment of Neurodegenerative Diseases: A Narrative Review, Current Alzheimer Research, June 2023, Bentham Science Publishers,
DOI: 10.2174/1567205020666230911125646.
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