What is it about?
Since 1965, Phytolacca dodecandra L’Herit (Endod) has been a research focus around the world mainly due to its pronounced activities against vectors that cause schistosomiasis. Scientists have identified many useful metabolites from the plant with promising potentials in drug discovery. In this review, we comprehensively reviewed the major phytochemicals isolated from the plant and their pharmacological activities.
Photo by Michael Longmire on Unsplash
Why is it important?
The World Health Organization recognized schistosomiasis as one of the neglected tropical diseases and scientists are still looking for promising drugs/vaccines/treatments. This review will typically provide possible alternatives and a re-think on the potential of the plant and its phytochemicals in this regard.
Read the Original
This page is a summary of: Triterpenoid and Saponin Rich Phytolacca dodecandra L’Herit (Endod): A Review on Its Phytochemistry and Pharmacological Properties, Mini-Reviews in Medicinal Chemistry, January 2021, Bentham Science Publishers, DOI: 10.2174/1389557520666200617110241.
You can read the full text:
Science from the third world: The Example of Endod in overcoming Obstacles
Aklilu Lemma (PhD) won the 1989 "The Righ Livehood Award" (aka the Alternative Nobel Prize) for discovering and campaigning relentlessly for an affordable preventative against bilharzia. His acceptance speech will provide readers his personal experiences in discovering the potential of Phytolacca dodecandra against schistosomiasis.
The following have contributed to this page