What is it about?

An imbalance caused in functioning of bone remodelling process leads to osteoporosis which is characterised by bone fractures, reduced bone strength and weak or enlarged bones. Osteoporosis is difficult to detect unless a person is met with an accident that may result in fracture. Thus, people of 45+ age group should have a regular check up and must have high calcium intake. Nanotechnology is playing such a vital role in detecting the biomarkers of bone formation and bone resorption for early detection of disease. Nowadays, nanotechnology has made it possible to direct target the osteoblasts cells for bone formation process and osteoclast cells for bone resorption.

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Why is it important?

This article includes all the recent studies of last 6-7 years in which researchers used nanotechnology for targeting osteoclast and osteoblast cells. Use of nanotechnology for detection and management of osteoporosis is well defined in this article.

Perspectives

This article well defines the use of nanotechnology in disease targeting but there are some side effects or challenges associated with it. This article may be a great help to researchers for filling gap and challenges in building a novel drug delivery system for direct targeting to bones for management of osteoporosis.

Malkiet Kaur
Chitkara University

Read the Original

This page is a summary of: Nanotechnology for Targeted Drug Delivery to Treat Osteoporosis, Current Drug Targets, January 2023, Bentham Science Publishers,
DOI: 10.2174/1389450123666221004124040.
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