Functionalized magnetic nanostructures for anticancer therapy

Eugenia Teodor, Florentina Gatea, Anton Ficai, Gabriel Radu
  • Current Drug Targets, February 2016, Bentham Science Publishers
  • DOI: 10.2174/1389450117666160208145835

What is it about?

In the last years, the production and applications of nanoparticles based on iron oxides in the field of biomedicine presented a great interest due to their particular properties. Because of the expansion of the pharmaceutical industry numerous new systems for drugs delivery have appeared, and those centered on magnetic nanoparticles are in a particular attention and in different promising developmental stages. The synthesis of these nanostructures with magnetic properties implies very simple assembling procedures and presents one of the lowest cytotoxic profiles. Magnetic nanostructures displayed possible appliance in a large diversity of biotechnological and medical fields, both for diagnose and therapy. In this mini review, some representative, interesting and feasible magnetic nanostructures obtained recently (from last 5-6 years) with possible use in antitumor/anticancer therapy are presented. Different types of magnetic nano-carriers loaded with different antitumor/anticancer agents and the cases tested in vivo are considered.

The following have contributed to this page: Dr Eugenia Dumitra Teodor and Prof.dr.eng Gabriel Lucian RADU