What is it about?
The review is aimed to show the advantages of using mutant and chemically modified porins for obtaining detailed information about molecular mechanisms that underlie the non-specific transmembrane diffusion.
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Why is it important?
Generalization of data regarding the effects of the point substitutions and the external loop deletions on electrophysiological properties of general porins will be useful for researchers in the field of integral membrane proteins.
Perspectives
I hope that the publication of the review will help in the study of the functional properties of novel porins of terrestrial and marine microorganisms.
Olga Novikova
G.B. Elyakov Pacific Institute of Bioorganic Chemistry
Read the Original
This page is a summary of: Modified and Mutant Porins in the Study on Molecular Basis of Non- Specific Diffusion, Current Protein and Peptide Science, January 2017, Bentham Science Publishers,
DOI: 10.2174/1389203717666160905145514.
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