What is it about?
CypD is localized in the mitochondrial transition pore, is a mitochondrial chaperone that has been shown to regulate mitochondrial function. This review focuses on the role of CypD in regulating mitochondrial function and provides a brief introduction to the relevant pathways as well as mechanisms, which provides new perspectives for related diseases.
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Why is it important?
We have conducted a literature review on mitochondrial diseases related to CypD, and we are also exploring the changes in mitochondrial function in drug-induced liver injury, delving into the role played by CypD, and providing a theoretical basis for drug-induced liver injury and mitochondrial related diseases.
Read the Original
This page is a summary of: Cyclophilin D-mediated Mitochondrial Permeability Transition Regulates Mitochondrial
Function, Current Pharmaceutical Design, March 2023, Bentham Science Publishers, DOI: 10.2174/1381612829666230313111314.
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