What is it about?
Cervical cancer is one of the most common cancers in women. Despite new methods and drugs to treat cervical cancer and the good results obtained with them, there is a wide range of chemicals and natural products that have not yet been studied and tested as anticancer agents. - The novel reduced salicylaldimine derivative L2b with remarkable anti-cancer potential. - For the first time, the cytotoxic properties of L2b were studied in seven different cell lines at different concentrations.
Photo by Louis Reed on Unsplash
Why is it important?
- For the first time, the apoptotic, cytotoxic and genotoxic properties of L2b were investigated in the cervical cancer cell line HeLa at different concentrations. - The current original study was performed using standard genotoxic, apoptotic, and cytotoxic assays, such as single-cell gel electrophoresis assay (Comet assay), DNA fragmentation ladder, acridine orange assay for DNA damage, and ELISA for measuring apoptosis.
Read the Original
This page is a summary of: ROS-mediated Genotoxicity and Apoptosis Induced by a Novel Salicylaldimine
Derivatives in Human Cervical Cancer Cells, Current Medicinal Chemistry, October 2023, Bentham Science Publishers, DOI: 10.2174/0929867330666221026162452.
You can read the full text:
The following have contributed to this page