What is it about?

Our study introduces VG111, a groundbreaking topical antimicrobial agent (having activity against MRSA, multi drug resistant Gram(-) bugs like Acinetobacter, Pseudomonas and others), optimized to heal any infective wound that resist conventional treatments. This novel natural product formulation not only heal wounds rapidly but also promotes natural skin regeneration without the adverse side effects often associated with conventional therapies like scars etc. VG111 stands out by eliminating the need for systemic antibiotics in treating localized infections, showcasing a significant efficacy in wound management through the promotion of healthy tissue growth obviating the need of graft.

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Why is it important?

Diabetic foot ulcers (DFUs) and pressure ulcers (PUs) present severe global health challenges with prevalence rates of 3-13% and 8.8-53.2%, respectively. The risk escalates in diabetic patients, often leading to lower limb amputations and exacerbated bedsores, particularly post-surgery. Shockingly, a lower limb is amputated every 30 seconds globally, illustrating the acute need for effective interventions. India, facing the highest burden, sees a fifth of its diabetes-related foot disorders result in amputation. The development of VG111 is critical in this context. It promises a revolutionary approach to wound care, aiming to significantly reduce amputation rates, alleviate the extensive burden on healthcare systems, and vastly improve patient outcomes. This research not only addresses a dire need but also has the potential to transform the standard of care in treating chronic wounds, offering new hope to millions affected worldwide.

Perspectives

As a researcher deeply involved in the study of wound care, I have witnessed the distress and challenges faced by patients with non-healing ulcers. VG111 is not just a medical product; it's a beacon of hope for those who have struggled with traditional treatments. This innovation could redefine standards of care, providing a new, efficient solution that respects the body's natural healing mechanisms while actively combating infection.

Vikas Gautam
Postgraduate Institute of Medical Education and Research

Read the Original

This page is a summary of: A Novel Potential Treatment for Diabetic Foot Ulcers and Non-Healing Ulcers - Case Series, Infectious Disorders - Drug Targets, June 2024, Bentham Science Publishers,
DOI: 10.2174/0118715265260305231115112728.
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