What is it about?
Mn(III) complexes prepared from Schiff base can catalyze an oxidation of 3,5-DTBC to 3,5-DTBQ and 1,4-di hydroxy benzene to 1.4-di benzo quinone. The time of completion is measured by NMR spectroscopy for each. In presence of triethyl amine , the time is reduced to just 5 minutes while without base it is 45 to 90 minutes.
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Why is it important?
An efficient biomimic of catechol oxidase has been prepared using manganese and Schiff base ligand. The time required for completion of oxidation is reported. A base enhanced rate of catecholic oxidation is proved. A base mediated mechanism is reported
Perspectives
It is a pleasure to write this article as a co-corresponding author. For last many months, we were involved in preparing new catecholase active complexes varying auxiliary ligand and solvents. We wanted to explore the role of base on the mechanism and also substrates other then 3,5-di tertiary butyl catechol to record the response of the newly developed catalysts . What we observed that, 1,4-di hydroxy benzene may also be oxidised to quinone in the stipulated time. In future, we will try to increase the susbtrate scope and apply catalysts using transition metals other than manganese.
Sohini Sarkar
KIIT University
Read the Original
This page is a summary of: Study on the Catecholase Activity in the Presence of a Mn(III)-based Catalyst and Base, Current Organic Synthesis, January 2025, Bentham Science Publishers,
DOI: 10.2174/0115701794285802240219064947.
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