What is it about?
Alzheimer's is a complex disease and we need better models with which to test drugs as potential curative agents for Alzheimer's. This study suggests a new model for trying to understand the contributions of brain inflammation to Alzheimer's.
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Why is it important?
Alzheimer's is the most common type of dementia and there are no curative drugs available for Alzheimer's. One of the major stumbling blocks is the need for better models to test experimental drugs. This study suggests such a model.
Perspectives
The search for new drugs for Alzheimer's has been a personal goal for more than 30 years. We have been working on this problem, step by step. This study describes our efforts to improve models for evaluating experimental drugs.
Donald Weaver
University of Toronto
Read the Original
This page is a summary of: Development and Optimization of a Target Engagement Model of Brain
IDO Inhibition for Alzheimer’s Disease, Current Alzheimer Research, October 2023, Bentham Science Publishers,
DOI: 10.2174/0115672050283199240111111801.
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