What is it about?

It is a Meta-analysis about Zero-Profile, a new cervical device. We evaluated whether zero-profile anchored spacer (Zero-P) could reduce complication rates, while maintaining similar clinical outcomes compared to conventional plate-cage construct (PCC) in the treatment of cervical spondylosis

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Why is it important?

Biomechanical studies reported that Zero-P provided a similar stability to PCC in one level ACDF, although it might not provide adequate segmental stability in multilevel ACDF, the encouraging clinical outcomes were reported in not only one but also multiple level ACDF surgery. However, conflicting results existed in different studies with regard to complications, especially dysphagia. To verify the conclusion of clinical outcomes based on the latest high-quality studies for strong evidence, we systematically compared Zero-P with PCC in terms of clinical outcomes and incidence of major complications in the treatment of one- or multiple- levels cervical spondylosis.

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This page is a summary of: Comparison of zero-profile anchored spacer versus plate-cage construct in treatment of cervical spondylosis with regard to clinical outcomes and incidence of major complications: a meta-analysis, Therapeutics and Clinical Risk Management, September 2015, Dove Medical Press,
DOI: 10.2147/tcrm.s92511.
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