What is it about?
This review covers the neurokininergic neural pathways involved in reward and addiction. We then cover potential drug targets and compounds currently in the pipeline that may be efficacious in combating addiction.
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Why is it important?
Addiction is a problem costing the U.S. over $700 billion per year. Understanding how addiction manifests is an important concept in preventing unnecessary loss of life and loss of quality of life. Neurokinins such as substance p play a crucial role in propagating the reward signal for drugs of abuse.
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This page is a summary of: The pharmacology of neurokinin receptors in addiction: prospects for therapy, Substance Abuse and Rehabilitation, September 2015, Dove Medical Press,
DOI: 10.2147/sar.s70350.
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