What is it about?

About the present role of palbociclib - the first in this class CDK4/6 inhibitor-, in the treatment of ER+ve/HER2-ve locally advanced and metastatic breast cancer

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Why is it important?

Represents a new therapeutic option

Perspectives

The development of CDK4/6 inhibitors and the introduction of palbociclib into clinical practice, represent an important addition to the therapeutic armamentarium in metastatic breast. There are several therapeutic choices available for ER+ve/HER2-ve advanced breast cancer, but adding palbociclib to hormone therapy is an option with strong efficacy data.

MD,PhD Katalin BK Boér
Szent Margaret Hospital

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This page is a summary of: Impact of palbociclib combinations on treatment of advanced estrogen receptor-positive/human epidermal growth factor 2-negative breast cancer, OncoTargets and Therapy, October 2016, Dove Medical Press,
DOI: 10.2147/ott.s77033.
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