What is it about?
up to our knowledge, this is the first report studying the association of IL-10 haplotype with breast cancer risk events among Jordanian females. The most frequent IL-10 haplotype among Jordanian breast cancer females is ACC haplotype. Patients carrying the ACC haplotype are associated with higher positive estrogen and progesterone receptors and advanced breast cancer grade and stage.
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Why is it important?
this is a unique research that show the association of IL-10 haplotype with breast cancer risk
Perspectives
This article is important because patients with certain ACC IL-10 haplotypes had lower survival rate in the Kaplan–Meier survival plot compared to those with non-ACC haplotype.
manar Atoum
Hashemite University
Read the Original
This page is a summary of: ACC interleukin-10 gene promoter haplotype as a breast cancer risk factor predictor among Jordanian females, OncoTargets and Therapy, June 2016, Dove Medical Press,
DOI: 10.2147/ott.s101628.
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