What is it about?
Photoreceptor outer segment length within the irradiated area was significantly decreased by 3.9% at 1 month compared with that before modified PDT and returned to baseline length at 3 and 6 months.
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Why is it important?
Photoreceptor outer segment (PROS) length is strongly correlated with the best-corrected visual acuity (BCVA) after idiopathic epiretinal membrane surgery and in patients with diabetic macular edema. Thus, PROS length is considered an important parameter for deducing retinal function. The photodynamic thirapy (PDT) causes choriocapillaris damage and choroidal vascular remodeling. PROS is adjacent to choroid. Hence, change of PROS length after PDT is important.
Perspectives
PDT depresses the choroid and the choroidal change influences PROS length and temporally suppress visual acuity.
Professor Hidenori Takahashi
Jichi Ika Daigaku
Read the Original
This page is a summary of: Changes of outer retinal microstructures after photodynamic therapy for chronic central serous chorioretinopathy, Clinical Ophthalmology, August 2017, Dove Medical Press,
DOI: 10.2147/opth.s139288.
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