What is it about?
The symptoms of catatonia have been reported to be similar to the initial symptoms of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. Recently, this autoimmune limbic encephalitis has been noticed by many psychiatrists.
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Why is it important?
When a patient showed catatonic symptoms, we should screen for anti-NMDAR antibodies in cerebrospinal fluid samples using a cell-based assay. This encephalitis is expected to be in remission by early detection and treatment. We should be more cautious about catatonic symptoms of schizophrenia.
Perspectives
Further study of anti-NMDAR antibody and its related encephalitis would give essential clues for the research of schizophrenia, catatonia, and atypical psychosis.
Dr Tetsuo Shimizu
Akita University Graduaye School of Medicine
Read the Original
This page is a summary of: N-Methyl-D-aspartate receptor antibody could be a cause of catatonic symptoms in psychiatric patients: case reports and methods for detection, February 2017, Dove Medical Press,
DOI: 10.2147/ndt.s125800.
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