What is it about?
This study aimed to review and pool the current literature on intra-articular ozone injection in knee osteoarthritis (OA) patients.
Featured Image
Why is it important?
Knee osteoarthritis is a prevalent degenerative condition in which functional impairment is caused by mechanical and chemical stress against the joint; resulting in pain and decreased joint motion. Obese females above the age of 50 are the most vulnerable group. Osteoarthritis has accounted for the fourth most common cause of hospital admission in 2009 in the United States with the annual cost of 42.3 billion dollars. On the other hand, although there are many medications and non-pharmacologic treatments including exercise, orthotics or assistive devices, and physical agent modalities; none of them could modify the underlying condition. In fact, the only definite therapeutic option is total knee replacement surgery. Ozone has been recently proved to be beneficial in symptom relief during short periods.
Perspectives
Based on the current meta-analysis, intra-articular ozone injection efficacy was superior to placebo and equal to other control injections; Therefor ozone could be recommended as an efficient non-surgical treatment, durable for at least 3-6 months, in mild or moderate knee OA management, particularly among middle-aged women.
Dr Shahram Rahimi-Dehgolan
Tehran University of Medical Sciences
Read the Original
This page is a summary of: An investigation into the efficacy of intra-articular ozone (O2–O3) injection in patients with knee osteoarthritis: a systematic review and meta-analysis, Journal of Pain Research, October 2018, Dove Medical Press,
DOI: 10.2147/jpr.s175441.
You can read the full text:
Contributors
The following have contributed to this page
