What is it about?
A severe gonadotropin deficiency together with chronic estradiol deficiency leading to amenorrhea characterizes patients suffering from hypogonadotropic hypogonadism.In this article, we review the data reported in the literature to highlight the role and the efficacy of using recombinant gonadotropins, rFSH and rLH, in the treatment of women with severe LH/FSH deficiency.The results observed in the studies reported in this review suggest that recombinant gonadotropins are able to induce proper follicular growth, oocyte maturation, and eventually pregnancy in this group of women
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Why is it important?
In this article, we review the data reported in the literature to highlight and emphasize the role and the efficacy of using recombinant gonadotropins, rFSH and rLH, in the treatment of women with severe LH/FSH deficiency
Perspectives
This article has a great value and high scientific contribution to assisted reproduction technology and how to manage women with severe LH/FSH deficiency. Further, it highlights that the clinical use of recombinant gonadotropins in this type of patients has given more insight into some endocrinological aspects of ovarian function that have not yet been fully understood.reproduction field
Dr Helmy Selman
One day Medical Center
Read the Original
This page is a summary of: Profile of follitropin alpha/lutropin alpha combination for the stimulation of follicular development in women with severe luteinizing hormone and follicle-stimulating hormone deficiency, International Journal of Women s Health, May 2016, Dove Medical Press,
DOI: 10.2147/ijwh.s88904.
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