What is it about?
Nanotechnology has been used in cancer treatments because of the possibility of destroying cancer tumors with minimal damage to healthy tissue and organs. Gold nanoparticles have been employed for cancer detection and treatment; however, it is not clear how they interact with normal and cancer cell membranes. In this paper we demonstrated that AuNPs: 1) are capable of emitting fluorescence, without the need for a fluorescent biomarker, 2) can interact with the cancer cell membrane that increases its roughness, phenomena that can enhance their uptake; 3) reach the nuclei as fast as 6 hours of incubation (if you have the chance to see the video, it is amazing!!!)
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Why is it important?
Our results will provide bases to understand the molecular and nanometric process of the use of Gold Nanoparticles in the treatment of breast cancer and other diseases.
Read the Original
This page is a summary of: Increasing roughness of the human breast cancer cell membrane through incorporation of gold nanoparticles, International Journal of Nanomedicine, October 2016, Dove Medical Press,
DOI: 10.2147/ijn.s108768.
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