What is it about?
Adipose derived stem cells (ADSCs) are an attractive cell source for tissue engineered skeletal muscle, considering the relatively easy access to ADSCs and a diminishing stem cell population in older patients and limited scaling ability of MDCs.
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Why is it important?
VML injuries repaired with either MDCs or ADSCs displayed typical hallmarks of tissue regeneration such as neo-tissue formation, cell fusion, fiber formation and scaffold remodeling. ADSCs also appeared to participate in vascularization.
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This page is a summary of: Evaluation of adipose-derived stem cells for tissue-engineered muscle repair construct-mediated repair of a murine model of volumetric muscle loss injury, International Journal of Nanomedicine, April 2016, Dove Medical Press,
DOI: 10.2147/ijn.s101955.
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