What is it about?
To identify the role of NKA, SPTA and drebrin in the erythrocyte membranes obtained from the blood of patients with neurodegenerative disorders (NDs) subjected to motor impairment such as Parkinson’s disease, amyotrophic lateral sclerosis, ataxia and dementia.
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Why is it important?
We observed a significant reduction in the expressions of NKA, SPTA and drebrin when compared to control and significant variations among the recruited ND samples. On correlating, we found a significant relationship between the expressions and the clinical features such as bradykinesia. Thus, we suggest that the reduction in the expressions of NKA, SPTA and drebrin could function as tools of assessment and speculate the particular neurodegenerative condition.
Perspectives
Working with the patients and writing this article is really a good learning curve
THAMILPAVAI ARULNAMBI
Madras Medical College
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This page is a summary of: Erythrocyte membrane in the evaluation of neurodegenerative disorders, Degenerative Neurological and Neuromuscular Disease, October 2017, Dove Medical Press,
DOI: 10.2147/dnnd.s143989.
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