What is it about?
COPD is a lung disease in most cases caused by cigarette smoking and has recently been recognized as a systemic inflammatory disease. Osteoporotic fractures, particularly vertebral fractures are very common in COPD patients, but the mechanism is not completely understood. This review explains risk factors and possible mechanisms of COPD-associated osteoporosis.
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Why is it important?
We emphasize that osteoporosis in COPD is caused by not only decreased bone mineral density but also impaired bone quality. And we propose routine screening and timely interventions for this extremely under-treated disease.
Perspectives
Most reviews on COPD-associated osteoporosis in the past were written by pulmonologists. This review is unique in that bone metabolic changes are summarized in a comprehensive manner from a viewpoint of endocrinologist in the bone field.
Professor Daisuke Inoue
Teikyo University Chiba Medical Center
Read the Original
This page is a summary of: COPD and osteoporosis: links, risks, and treatment challenges, International Journal of Chronic Obstructive Pulmonary Disease, March 2016, Dove Medical Press,
DOI: 10.2147/copd.s79638.
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