What is it about?
The aim of this study was to measure various microparticles from different cellular origins in COPD patients with a reliable flow cytometric method for diagnostic purposes.
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Why is it important?
A novel observation of our study that not only endothelial derived microparticles (MPs) are elevated in exacerbated COPD but also platelet-derived CD41+ and CD42a+ and monocyte-derived CD14+ MPs also take a significant part in COPD exacerbations.
Perspectives
Elevated microparticle values in exacerbated COPD patients may help to recognize disease progression and to start adequate therapy to achieve a better clinical outcome.
Tihamer Molnar
University of Pecs, Medical School, Hungary
Read the Original
This page is a summary of: Role of microparticles derived from monocytes, endothelial cells and platelets in the exacerbation of COPD, International Journal of Chronic Obstructive Pulmonary Disease, November 2018, Dove Medical Press,
DOI: 10.2147/copd.s175607.
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