Smoking-related interstitial fibrosis combined with pulmonary emphysema: computed tomography-pathologic correlative study using lobectomy specimens

  • Hideji Otani, Tomonori Tanaka, Kiyoshi Murata, Junya Fukuoka, Norihisa Nitta, Yukihiro Nagatani, Akinaga Sonoda, Masashi Takahashi
  • International Journal of Chronic Obstructive Pulmonary Disease, July 2016, Dove Medical Press
  • DOI: 10.2147/copd.s107938

CT of smoking-related interstitial fibrosis

What is it about?

Although smoking-related interstitial fibrosis is thought to be an incidental finding seen in smokers, it is more frequent finding than is expected. Smoking-related interstitial fibrosis combined with pulmonary fibrosis is demonstrated on thin-section CT as thin-walled, clustered cysts with irregular size and shape accompanied by surrounding mild ground-glass opacity. This finding is different from honeycombing.

Why is it important?

Differentiation of honeycombing from smoking-related interstitial fibrosis with combined with pulmonary emphysema is important for CT diagnosis of usual interstitial pneumonia. The results of this article may help this differentiation.


Kiyoshi Murata

Smoking-related interstitial fibrosis combined with pulmonary emphysema should be understood to be an independent finding from progressive fibrotic interstitial pneumonia such as usual interstitial pneumonia, although both pathological conditions can co-exist.

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The following have contributed to this page: Professor Junya Fukuoka and Kiyoshi Murata

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