What is it about?
Endothelial dysfunction is involved in the pathogenesis of cerebral small vessel disease, however, it is not clear if specific biomarkers related to endothelial function are associated with radiological progression of small vessel disease.
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Why is it important?
Our data supports the concept that endothelial dysfunction modulates the radiological progression of small vessel disease and white matter lesions and lacunes are associated with different inflammatory markers.
Perspectives
Stroke biomarkers could be used as a guiding tool for more effective personalized therapy.
Jacek Staszewski
Military Institute of Medicine
Read the Original
This page is a summary of: IL-6, PF-4, sCD40 L, and homocysteine are associated with the radiological progression of cerebral small-vessel disease: a 2-year follow-up study, Clinical Interventions in Aging, June 2018, Dove Medical Press,
DOI: 10.2147/cia.s166773.
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