What is it about?
Clinical and laboratory features of intestinal tuberculosis
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Why is it important?
Gastrointestinal tuberculosis and Crohn’s disease are granulomatous diseases of the intestine and have a close resemblance in terms clinical, radiological, endoscopic, surgical, and histological features. Thus, differential diagnosis of these 2 conditions remains a major challenge to clinicians.If patients are misdiagnosed with GITB, toxicity may result from unnecessary anti-TB therapy and treatment of the primary disease (ie, CD) gets delayed
Perspectives
Although histology is helpful in ruling out other conditions, TB-specific findings such as caseating granuloma and AFB are rarely seen. Instead, TBPCR has the highest diagnostic accuracy followed by BACTEC culture. Furthermore, the majority of colonic lesions, including strictures, resolve with anti-TB treatment, suggesting that strictures are inflammatory rather than fibrotic. Follow-up colonoscopy is not required in those who have symptomatic improvement after anti-TB treatment.
Vipul Yagnik
Ronak endolaparoscopy and general surgical hospital
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This page is a summary of: Clinical and laboratory features of intestinal tuberculosis, Clinical and Experimental Gastroenterology, March 2018, Dove Medical Press,
DOI: 10.2147/ceg.s154235.
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