What is it about?
Thrombophilia increases the risk of pregnancy- postpartum and oral contraceptive-associated venous thrombosis, especially in women with combined or homozygous defects. Factor V Leiden and prothrombin G20210A gene mutations are the most common forms of heritable thrombophilia. Both these mutations have a distinctive worldwide distribution are the most prevalent among Caucasians and middle Easterners, and have a moderate to rare prevalence among other population Aim: In this study, we aimed to analyze the genetic and acquired risk factors for deep vein thrombosis (DVT) of the lower extremities among Sudanese women. In this study, we aimed to analyze the genetic and acquired risk factors for deep vein thrombosis (DVT) of the lower extremities among Sudanese women.
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Why is it important?
Conclusion: Risk factors that most significantly affected patients in the 18–45 years age group were pregnancy and oral contraceptive usage, whereas those that most significantly affected patients in the 66–90 years age group were immobility, heart disease, and history of DVT.
Perspectives
The risk of DVT increased in pregnancy because of a more hypercoagulable state, and likely adaptation against fatal postpartum bleeding tendency additionally, pregnant women with genetic risk factors are subject to increased risk for thrombosis. Our recent study explained rich informations about the genetic prevalence of thrombosis among susceptible females if any to reduce mortality and morbidity
mahmoud abdalla
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This page is a summary of: Risk factors for deep vein thrombosis of lower extremities in Sudanese women, Vascular Health and Risk Management, August 2018, Dove Medical Press,
DOI: 10.2147/vhrm.s170556.
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