What is it about?

SLE is a disease with a thousand presenting feature. We presented a girl with bilateral ascending muscular weakness ( Guillan-Barre syndrome) who did not respond to conventional treatment and with chronicity (CIDP), we performed more work-up and found the underlying disease known as systemic lupus erythematosus.

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Why is it important?

We want to emphasis on a teaching point: in approach to any atypical or resistant neuropsychiatric manifestations, the physician should aware of autoimmune disorders especially SLE.


It's always my wish that physicians in approach to every child with multi-system manifestations, especially in teenage girls, consider the rheumatic diseases, especially lupus and vasculitis in the differential diagnosis. I hope this article will be a tool for more attention to my dear colleagues.

Vadood Javadi Parvaneh
Shahid Beheshti University of Medical Sciences

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This page is a summary of: Guillain–Barre syndrome as the first manifestation of juvenile systemic lupus erythematosus: a case report, Open Access Rheumatology Research and Reviews, April 2019, Dove Medical Press, DOI: 10.2147/oarrr.s204109.
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