Bepotastine besilate ophthalmic solution 1.5% for alleviating nasal symptoms in patients with allergic conjunctivitis

Megan E Cavet, Paul J Gomes, Warner W Carr, Jon I Williams
  • Journal of Asthma and Allergy, March 2018, Dove Medical Press
  • DOI: 10.2147/jaa.s160687

Improvement in allergic nasal symptoms following application of bepotastine besilate as an eyedrop

What is it about?

It was found that the anti-histamine bepotastine besilate which used to treat ocular allergy symptoms (itching and redness) also improved allergic nasal symptoms, both in well-controlled trials in the clinic and in an environmental (field) test during ragweed season.

Why is it important?

Anti-histamine eyedrops are approved for treating ocular symptoms of allergy and not for associated symptoms. The results described in this paper offer opportunities for further clinical development of eyedrops to treat allergic symptoms both in the eye and in the nasal passages.


Jon Williams
Valeant Pharmaceuticals International Inc

It was a pleasant and rewarding surprise to me to see that the development pathway for an anti-histamine eyedrop to treat ocular allergy symptoms could be adapted potentially for treating nasal allergy symptoms (much as has been done for several corticosteroids), and that the eyedrop may be all that is necessary to quell both ocular and nasla llergy symptoms.

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The following have contributed to this page: Jon Williams