Mineralized Amino Acid into Yolk-shell Microspheres Used for Treatment of Bone Infection
What is it about?
Amino acid (L-lysine (Lys)) was mineralized into Yolk-shellyolk-shell structured CaCO3 microspheres. The as prepared Lys encapsulated CaCO3 microspheres (Lys@CaCO3 MSs) were used as micro-drug to improve acidic environment of osteomyelitis caused by bacterial infection and promote osteoblast proliferation under oxidative stress.
Why is it important?
Treatment of infection within bone is difficult, and conventional surgical treatment brings great pain to the patients physically and mentally, . it It is very urgent that to develop injectable nano and/or micro medicine for minimally invasive treatment of osteomyelitis.
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