What is it about?
To the best of our knowledge, this is the first study to assess resistance associated substitutions of Hepatitis C virus genotype 4a following non-response to treatment with direct acting antiviral agents.
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Why is it important?
The study results may help in tailoring future therapy for patients with no response to DAA drugs.
Perspectives
This work should be extended using larger sample size and to include relapsers to multiclass drug users.
Professor Monkez M Yousif
Zagazig University
Read the Original
This page is a summary of: Deep-sequencing study of HCV G4a resistance-associated substitutions in Egyptian patients failing DAA treatment, Infection and Drug Resistance, September 2019, Taylor & Francis,
DOI: 10.2147/idr.s214735.
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