inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD
What is it about?
In our previous papers, with explained that vessel changes in chronic obstructive pulmonary disease (COPD) include increased numbers of vessels in the area immediately beneath the epithelium (called reticular basement membrane) and reduced number of vessels in the deeper mucosa (called lamina propria). The current study assessed the effect of inhaled corticosteroids on these vessel changes.
Why is it important?
COPD is a very common respiratory disease. Inhaled corticosteroids are routinely used in patients with COPD. However, their effects on vascular remodelling, which is defined as vessel changes in the airways, has never been studied in a double-blinded, placebo controlled trial. Our study is the first of this type that assessed the effects of treatment in vessel remodelling. in COPD.
The following have contributed to this page: Dr Shakti Dhar Shukla, Dr Sukhwinder Singh Sohal, Dr Amir Soltani, and Eugene Walters