What is it about?
S100A16 belongs to the Ca2+ binding protein. We have shown that it can promote the chemoresistance of bladder cancer based on chemoresistant cell line. This may be related to its anti-apoptosis effect.
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Why is it important?
Our findings show that S100A16 can promote the chemoresistance of nonmuscle invasive bladder cancer through anti-apoptosis pathway, thus providing a new strategy to prevent or reverse the bladder cancer chemoresistance.
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This page is a summary of: S100A16 regulated by Snail promotes the chemoresistance of nonmuscle invasive bladder cancer through the AKT/Bcl-2 pathway, Cancer Management and Research, March 2019, Dove Medical Press, DOI: 10.2147/cmar.s196450.
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