IL-6, PF-4, sCD40 L, and homocysteine are associated with the radiological progression of cerebral small-vessel disease: a 2-year follow-up study

Jacek Staszewski, Renata Piusińska-Macoch, Bogdan Brodacki, Ewa Skrobowska, Adam Stepien
  • Clinical Interventions in Aging, June 2018, Dove Medical Press
  • DOI: 10.2147/cia.s166773

A study of biomarkers associated with the radiological progression of cerebral small vessel disease.

What is it about?

Endothelial dysfunction is involved in the pathogenesis of cerebral small vessel disease, however, it is not clear if specific biomarkers related to endothelial function are associated with radiological progression of small vessel disease.

Why is it important?

Our data supports the concept that endothelial dysfunction modulates the radiological progression of small vessel disease and white matter lesions and lacunes are associated with different inflammatory markers.

Perspectives

Jacek Staszewski (Author)
Military Institute of Medicine

Stroke biomarkers could be used as a guiding tool for more effective personalized therapy.

The following have contributed to this page: Jacek Staszewski