What is it about?

“PaCO2 = PvCO2 (= about 50mmHg)” is the condition to stop hiccups. If you are able to create that condition, hiccups stop because functions of the medulla in which the epicenter of hiccup is located is strongly suppressed. Please see the commentary from Dr.GA Petroianu; “Abolishing the venous‐arterial CO2 gradient as treatment for singultus: Commentary on Obuchi et al, 2018.”

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Why is it important?

This is the first report that mentioned the specific conditions to make hiccups stop. Using this method, you are able to conduct other experiments about hiccups with MRI, electrocehpalography and so on. Please find a further truth of the brain.


The findings can be a clue to reveal another mystery of the brain.

Dr. Toshiro Obuchi

Read the Original

This page is a summary of: Medullar impairment resolves hiccups, Journal of Thoracic Disease, June 2018, AME Publishing Company, DOI: 10.21037/jtd.2018.06.21.
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