What is it about?
A new series of 1,3,4-oxadiazoles, have been synthesized from amoxicillin on treatment with various chemicals, the prepared 1,3,4-oxadaizoles derivatives(9-13) reacted with acryloyl chloride to prepared acryl monomers (14-18) that polymerized to acryl polymers of amoxicillin derivatives (19-23). The structures of compounds (2-23) have been elucidated by FT-IR and 1HNMR, furthermore some compounds (9-13) and (19-23) were screened for in vitro antibacterial activity against gram positive and gram negative bacteria. The compounds show inhibitory action against test organism
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Why is it important?
The structures of compounds have been elucidated by FT-IR and 1HNMR, furthermore some compounds were screened for in vitro antibacterial activity against gram positive and gram negative bacteria. The compounds show inhibitory action against test organism
Perspectives
I hope this article help the researchers to improve this drug and make it more active
khalida Ali thejeel
AL- karkh university of science
Read the Original
This page is a summary of: Synthesis, Characterization and Polymerization of 1,3,4- Oxadiazole Derivatives of Amoxicillin and Evaluation Antibacterial Activities, International Journal of Current Microbiology and Applied Sciences, February 2016, Excellent Publishers,
DOI: 10.20546/ijcmas.2016.502.058.
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