Importance of physical activity in maintaining disease stabilization in pancreatic cancer

What is it about?

Locally advanced or metastatic adenocarcinoma is an incurable disease and the prognosis is inexorably fatal. The treatments currently available such as chemotherapy and radiotherapy have a marginal effectiveness with palliative purposes. However, there are other elements that can negatively affect the progression in general such as the depressive state of the individual through the suppression of the immune system which facilitates the progression of the disease. There are studies that have shown how constant and moderate physical activity can be able to positively affect immune depression with an impact on the risk of recurrence and death from malignancies or cardiovascular diseases. Furthermore, chemotherapy also seems to interact positively with the immune system and therefore the response to treatment does not seem to be only the result of direct killing of the neoplastic cells but also secondary to the positive modification of the innate and adaptive immune system.

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Why is it important?

Assuming that at the base of the positive progress of a patient suffering from inoperable pancreatic adenocarcinoma treated with chemo-radiotherapy there may be constant physical activity that led him to travel more than 15000 kilometers on foot, the likely impact on the immune system can be responsible for well-being with a survival of over seven years.

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