What is it about?

Acrylamide is a chemical substance, the utilization area of which is widespread. It is available in many places from various industries to laboratories, from daily food to cigarette smoke. Acrylamide, known as a neurotoxic agent since the middle of the 20th century, was found to form in foods in 2002. Acrylamide forms as a result of the reaction between asparagine and the reducing sugars such as fructose and glucose in the high-temperature processed foods.

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Why is it important?

The food ingredients, asparagine amount, food processing method, temperature, and other factors affect the amount of acrylamide to form in foods. After the discovery of acrylamide formation in foods, other effects of acrylamide became the subject of research. As a result of these studies, the effect of acrylamide on the testis, ovaries, liver lung, kidney, bowel organs has been revealed. Acrylamide is also categorized in the substances that are probably carcinogenic to humans by the International Agency for Research on Cancer. Although acrylamide was proven to be carcinogenic for experimental animals, there is no more definitive evidence for humans. Acrylamide exposure is inevitable in daily life. Acrylamide forms as a result of the majority of food processes. This may pose a risk for who exposes more to acrylamide-containing foods, especially for children.

Perspectives

In this review, the bodily effects of acrylamide were discussed and suggestions for its protection modalities were provided, which was previously shown to be harmful but its exact potential toxicity has not yet been fully understood.

Sedat Kacar
Eskisehir Osmangazi Universitesi

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This page is a summary of: Bir Çoklu Organ Toksini: Akrilamit, OSMANGAZİ JOURNAL OF MEDICINE, January 2018, Osmangazi Journal of Medicine,
DOI: 10.20515/otd.323209.
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