What is it about?
The maternal thyroid dysfunctions (maternal hypothyroidism) during the gestation may cause several disorders in the neonatal cognitive and social behaviors. These effects might depend on the severity of thyroid disorders, sex type and developmental period.
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Why is it important?
Females are more susceptible to developing internalizing problems while males are reliably more vulnerable to developing externalizing problems (biological or environmental risk factors). However, this link is weak and the fundamental mechanisms undistinguishable.
Perspectives
Additional studies are necessary to examine whether the individual variations in THs trajectories (FT4 and TSH levels) during the gestation will be a better indicator of neonatal cognitive behavioral disorders than maternal THs levels evaluated at one trimester of pregnancy. In addition, several studies are warranted to examine whether there are sex differences in the interactions between the maternal THs trajectories and neonatal cognitive behavioral disorders.
Full Professor Ahmed R. G.
Division of Anatomy and Embryology, Zoology department, Faculty of Science, Beni-Suef University, Egypt.
Read the Original
This page is a summary of: Maternal Thyroid Hormones Trajectories and Neonatal Behavioral Disorders, ARC Journal of Diabetes and Endocrinology, January 2017, ARC Publications Pvt Ltd.,
DOI: 10.20431/2455-5983.0302003.
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