What is it about?
Ketodex is a combination of ketamine and dexmedetomidine. Ketamine, an old intravenous anesthetic, is a non-narcotic and non-barbiturate drug. It has several properties of the ideal anesthetic agent. However, ketamine can produce psychological adverse effects. Dexmedetomidine has analgesic, amnesic, sedative, and anxiolytic properties.
Featured Image
Photo by Ibrahim Boran on Unsplash
Why is it important?
A distinct advantage of dexmedetomidine is the maintenance of respiratory force and preserved airway patency. It converges on a natural sleep pathway, activating pathways that promote endogenous non-rapid eye movement sleep to exert its sedative effect. However, dexmedetomidine can produce bradycardia and hypotension.
Perspectives
A combination of ketamine and dexmedetomidine has several benefi ts in the terms of hemodynamic stability, absence of respiratory depression, postoperative analgesia, and recovery. Several previous studies have been demonstrated the therapeutic utility of the combination of ketamine and dexmedetomidine.
Professor Somchai Amornyotin
Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University
Read the Original
This page is a summary of: Use of a combination of ketamine and dexmedetomidine (Ketodex) in different clinical cases, Journal of Addiction Medicine and Therapeutic Science, June 2020, Peertechz.com,
DOI: 10.17352/2455-3484.000036.
You can read the full text:
Resources
Contributors
The following have contributed to this page
