What is it about?

This prospective study documents that blood pressure during sleep, but not during awakening of measurements obtained at the clinic, is a significant prognostic marker for the risk of developing chronic kidney disease (CKD). It also documents for the first time that decreasing sleep-time blood pressure actually reduces the risk for CKD.

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Why is it important?

The results provide, first, a method to quantify the individualized risk for CKD based on the determination of sleep-time blood pressure by ambulatory monitoring, the already recommended approach for proper diagnosis of hypertension; and second, a way to reduce such risk by specifically targeting sleep-time blood pressure by proper timed therapeutic intervention.

Perspectives

These findings, if confirmed and extended to other populations, might provide a proper method for preventing the development and progression of CKD, a highly prevalent condition.

Ramon Hermida
Universidade de Vigo

Read the Original

This page is a summary of: Sleep-Time Ambulatory BP Is an Independent Prognostic Marker of CKD, Journal of the American Society of Nephrology, April 2017, American Society of Nephrology,
DOI: 10.1681/asn.2016111186.
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