Effects of Zibotentan and Dapagliflozin on Fluid Retention in Patients with CKD

What is it about?

The article by Heerspink et al. offers valuable insights into the correlation between Zibotentan or Dapagliflozin and fluid retention. However, the use of the cox proportional hazards model in their analysis presents several limitations. The study may result in mixed censoring outcomes, and the assumption of constant hazard ratios over time may not hold.

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