What is it about?

This case emphasizes on the adverse consequence of phenytoin injection extravasation. In critically ill patients on vessopressor support may exacerbate the ischemia of the infused limb. Norepinephrine is known for intense vasoconstriction is very commonly used in septic patients in critically ill patients. This two drugs pharmacodynamics may cause more intensified response of phenytoin extravasation even with single dose injection.

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Why is it important?

the observed result may help us in reducing potentially devastating adverse effect of phenytoin extravasation

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This page is a summary of: Point to ponder while prescribing phenytoin sodium infusion in septic shock patients: A case-based discussion, Journal of Advanced Clinical and Research Insights, January 2016, Incessant Nature Science Publishers Pvt Ltd.,
DOI: 10.15713/ins.jcri.101.
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