Estrogen deficiency is a cancer risk factor for all sites of the body
What is it about?
Accumulation of oral cancer incidence among non-smoker, non-drinker elderly female patients is conspicuous. Structures of upper aerodigestive tract are moderately estrogen dependent; they are endangered by cancer development only in case of deep estrogen deficiency. By contrast, female reproductive organs have high estrogen demand and even a mild defect of estrogen surveillance may be cancer risk factor for them.
Why is it important?
Controversial results on the carcinogenic capacity of estrogen derive from the misinterpretation of the importance of estrogen signaling in cancer prevention.
The following have contributed to this page: professor Zsuzsanna Suba