Fast Determination of Cannabis metabolite with LC-MS/MS : ultra-fast chromatographic elution
What is it about?
A fast, reliable method has been developed for the determination of cannabis metabolite (THC-COOH) in urine, using LC—MS/MS. It could be detected in 1.75min in LC-MS/MS. Comprehensive validation was performed. Even 1.41 ng/mL could be detected usin this method. HorRat was calculated to assess the inter-day and inter-analyst precision values. Successful results were obtained with the CEDIA positive real samples containing cannabis.
Why is it important?
Cannabinoids are components of marijuana and its metabolite THC-COOH is excreted in the urine of the users. To detect if a suspected person has used cannabis, a fast, reliable, sensitive, simple method is needed fo4r routine analysis.
Perspectives
http://dx.doi.org/10.1556/1326.2017.29.2.09
The following have contributed to this page: Assoc. Prof. Dr. Beril ANILANMERT
