Unusual Recalcitrant Classic Kaposi’s Sarcoma in a Non-AIDS Yemeni Man: Is It a Zoonotic!

What is it about?

Abstract I report a case of a 43-year-old non-HIV infected Yemeni shepherd, who presented with a fungating, multipigmented plaque of several, purplish/dark-brownish, friable nodules on the right index finger, cutaneous dissemination, and lymphatic infiltrates. Chronicity, number and morphology of the lesions, local lymphatic infiltration and the characteristic histopathological findings were identical with Kaposi’s sarcoma (KS); the classic variant. Due to rarity of non human immunodeficiency virus (HIV)-associated KS, here I report a case of classic KS in an immunocompetent middle-aged Asian male. I also raise a question about human KS-associated herpesvirus (KSHV) and its zoonotic potential for cross-species infection.

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Why is it important?

Conclusion This report may open new avenues for the research of KS. To the best of author’s knowledge, such a case of KS has not been reported in Yemeni literatures. Awareness of KS clinic pathological features is important to avoid unnecessary interventions. Conflict of Interest Disclosure: None declared.