What is it about?
Schmidt’s syndrome also known as autoimmune polyglandular syndrome type 2 (APS type 2) is a rare endocrine disorder defined by the combined occurrence of Addison disease with autoimmune thyroid disease. The rarity of the condition and the atypical presentation of adrenal insufficiency and hypothyroidism often lead to misdiagnosis with life-threatening consequences for the patient. In this study we report an exhaustive monocentric analysis of 22 patients diagnosed with a Schmidt’s Syndrome.
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Why is it important?
Schmidt’s Syndrome is more likely to be associated with the female sex and young age. In our study, Hashimoto’s hypothyroidism was the first autoimmune disease discovered.
Perspectives
The presence of at least one component of the APS type 2 must lead to the autoimmune screening of the other diseases. This screening could avoid the triggering of an adrenal insufficiency in thyroid hormonal substitution
Taieb Ach
Hospital University Farhat Hached Sousse Tunisia
Read the Original
This page is a summary of: Clinical aspects of the schmidt's syndrome: a 14 years retrospective monocentric study, Endocrine Abstracts, May 2018, Bioscientifica,
DOI: 10.1530/endoabs.56.p162.
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